Protein Concentrators

Centrisart

Centrisart is a ready to use unit for small volume centrifugal ultrafiltration to separate proteins from low molecular weight substances in biological samples.

Centrisart features a unique design, ultrafiltration in the opposite direction to the centrifugal force. This is so effective in preventing premature blockage of the filter that even whole blood samples can be deproteinised. The ultrafiltrate is collected in the floater insert tube, where it is readily accessible without removing the tube.

Want some? Order HOT line 01536 523604

or buy online HERE

Vivaspin 500

100 to 600 µl samples
Vivaspin 500 µl centrifugal filter units offer a simple, one step procedure for sample preparation. They can effectively be used in fixed angle rotors accepting 2.2 ml centrifuge tubes.

The patented vertical membrane design and thin channel filtration chamber (US 5,647,990), minimises membrane fouling and provides high speed concentrations, even with particle laden solutions.

Want some? Order HOT line 01536 523604

or buy online HERE

Vivaspin 2

Vivaspin 0.4 to 2 ml
The new Vivaspin 2 bridges the gap between the 500 µl and 4 ml centrifugal concentrators. This device combines the speed of the classic Vivaspin products with low internal surface and membrane area for superior recoveries from very dilute solutions.

Available with a choice of PES, Cellulose Triacetate and Hydrosart membranes, Vivaspin 2 offers the highest flexibility for process optimisation.

Also unique to the Vivaspin 2, is the choice of directly pipetting the concentrate from the dead stop pocket built into the bottom of the concentrator, or alternatively reverse spinning into the concentrate recovery cap which can then be sealed for storage.

Both methods result in near total concentrate recoveries.

 Want some? Order HOT line 01536 523604

or buy online HERE

Vivaspin 4

1 - 4 ml samples
Vivaspin 4 ml concentrators are disposable ultrafiltration devices for the concentration of biological samples. Maximum initial sample volumes range from 1 ml to 4 ml. They can be effectively used in either swing bucket or fixed angle rotors accepting 15 ml centrifuge tubes.

The patented vertical membrane design and thin channel filtration chamber (US 5,647,990) minimises membrane fouling and provides high speed concentrations, even with particle laden solutions.

Vivaspin 4 is available with the high flux polyethersulfone membrane range which is recommended for most solutions.

Want some? Order HOT line 01536 523604

or buy online HERE

Vivaspin 6

2-6 ml samples
The Vivaspin 6 centrifugal concentrators have been developed to offer increased volume flexibility and performance.
Vivaspin 6 can process 6ml in either swing bucket or fixed angle rotors accepting standard 15ml conical bottom test tubes.

High speed and high performance
The Vivaspin 6 feature twin vertical membranes for unparalleled filtration speeds and 100X plus concentrations.  Remaining volume is easy to read off the printed scale on the side of the concentrator and the modified dead stop pocket further simplifies direct pipette recovery of the final concentrate.

 Want some? Order HOT line 01536 523604

or buy online HERE

Vivaspin 15

2 - 15 ml samples
The Vivaspin 15 concentrator is a disposable ultrafiltration device for use in fixed angle or swing bucket rotors accommodating 50 ml tubes. Vivaspin 15 is used for the concentration of biological samples in the 2 - 15 ml range. The innovative design (US Patent no. 5,647,990, second patent pending), simplicity, speed and exceptional concentrate recoveries are the main features of the concentrator.

In a single spin, 15 ml solutions can be concentrated up to 300x. Samples can be typically concentrated in 10-30 minutes with macromolecular recoveries in excess of 95%. The longitudinal membrane location and adjacent thin channel, provide optimum cross flow conditions even for particle laden solutions, the centrifugal force pulling particles and solids away from the membrane to the bottom of the device. Macromolecules collect in an impermeable 50 µl concentrate pocket integrally moulded below the membrane surface, thereby eliminating the risk of filtration to dryness.

 Want some? Order HOT line 01536 523604

or buy online HERE

Vivaspin 15R

2 - 15 ml samples
Vivaspin 15R is the latest member of the Vivaspin product family with all the unique features of Sartorius Stedim Biotech concentrators including a patented vertical membrane and a dead stop. Vivaspin 15R is targeting the volume segment 2 to 15 ml with a modified regenerated cellulose membrane; Hydrosart®. This membrane is ideal where extremely high recovery with very low adsorption is needed, for example in applications such as desalting and concentration of Ig fractions.

 Want some? Order HOT line 01536 523604

or buy online HERE

Vivaspin 20

5-20 ml samples
The Vivaspin 20ml centrifugal concentrators have been developed to offer increased volume flexibility and performance.

Vivaspin 20 handles up to 20ml in swing bucket centrifuges 14ml in 25° fixed angle rotors accepting 50ml centrifuge tubes. Featuring twin vertical membranes for unparalleled filtration speeds and 100X plus concentrations. Remaining volume is easy to read off the printed scale on the side of the concentrator and the modified dead stop pocket further simplifies direct pipette recovery of the final concentrate.

Process Flexibility
Vivaspin 20 is available with unique accessories and operating methods that are designed to provide more process flexibility and further time saving.

One Step Desalting
In this procedure following concentration, a diafiltration cup is filled with buffer and then spun one time to achieve 98% salt removal. This compares to the need for two spins to achieve the same result with the traditional refill and re-spin procedure.

The improved performance is due to the constant washing action of the buffer solution in the accessory cup as it replaces solvent and salts as they pass through the ultrafiltration membrane.

Gas Pressure Filtration
When an appropriate centrifuge is unavailable, or for single sample processing, Vivaspin 20 can be filled with up to 15ml and then pressurised for bench top concentration. For even faster processing, Gas pressure can be combined with centrifugal force. "Pressure-fugation" is particularly suitable for difficult or viscous samples such as serum, or when using a low process temperature which reduces filtration speed, and generally when minimum process time is essential.

 Want some? Order HOT line 01536 523604

or buy online HERE